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河南农村队列研究
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注册号:

Registration number:

ChiCTR-OOC-15006699 

最近更新日期:

Date of Last Refreshed on:

2018-04-15 

注册时间:

Date of Registration:

2015-07-06 

注册号状态:

预注册  

Registration Status:

Prospective registration  

注册题目:

河南农村队列研究 

Public title:

The Henan Rural Cohort Study 

注册题目简写:

 

English Acronym:

 

研究课题的正式科学名称:

河南省农村常见慢性非传染性疾病前瞻性队列研究 

Scientific title:

Prospectie Cohort Study on the Common Chronic Non-communicable Diseases in Rural areas of Henan Province 

研究课题代号(代码):

Study subject ID:

 

在二级注册机构或其它机构的注册号:

The registration number of the Partner Registry or other register:

 

申请注册联系人:

刘晓田 

研究负责人:

王重建 

Applicant:

Xiaotian Liu 

Study leader:

Chongjian Wang 

申请注册联系人电话:

Applicant telephone:

+86 13676900717 

研究负责人电话:

Study leader's telephone:

+86 15903670197 

申请注册联系人传真 :

Applicant Fax:

 

研究负责人传真:

Study leader's fax:

 

申请注册联系人电子邮件:

Applicant E-mail:

xtLIU2008@126.com 

研究负责人电子邮件:

Study leader's E-mail:

tjwcj2005@126.com 

申请单位网址(自愿提供):

Applicant website(voluntary supply):

 

研究负责人网址(自愿提供):

Study leader's website(voluntary supply):

 

申请注册联系人通讯地址:

河南省郑州市高新区科学大道100号郑州大学新校区公共卫生学院 

研究负责人通讯地址:

河南省郑州市高新区科学大道100号郑州大学新校区公共卫生学院 

Applicant address:

College of Public Health in Zhengzhou University; 100 Kexue Road, Gaoxin District, Zhengzhou, Henan, China 

Study leader's address:

College of Public Health in Zhengzhou University, 100 Kexue Road, Gaoxin District, Zhengzhou, Henan, China 

申请注册联系人邮政编码:

Applicant postcode:

450001 

研究负责人邮政编码:

Study leader's postcode:

450001 

申请人所在单位:

郑州大学公共卫生学院 

Applicant's institution:

College of Public Health in Zhengzhou University 

是否获伦理委员会批准:

是 

Approved by ethic committee:

Yes 

伦理委员会批件文号:

Approved No. of ethic committee:

[2015] MEC (S128) 

伦理委员会批件附件:

Approved file of Ethical Committee:

查看附件View

批准本研究的伦理委员会名称:

郑州大学生命科学伦理审查委员会 

Name of the ethic committee:

Zhengzhou University Life Sciences Ethics Committee 

伦理委员会批准日期:

Date of approved by ethic committee:

2015-03-06 

伦理委员会联系人:

 

Contact Name of the ethic committee:

 

伦理委员会联系地址:

 

Contact Address of the ethic committee:

 

伦理委员会联系人电话:

Contact phone of the ethic committee:

 

伦理委员会联系人邮箱:

Contact email of the ethic committee:

 

研究实施负责(组长)单位:

郑州大学公共卫生学院 

Primary sponsor:

College of Public Health in Zhengzhou University 

研究实施负责(组长)单位地址:

河南省郑州市高新区科学大道100号郑州大学新校区公共卫生学院 

Primary sponsor's address:

College of Public Health in Zhengzhou University; 100 Kexue Road, Gaoxin District, Zhengzhou, Henan, China 

试验主办单位(项目批准或申办者):

Secondary sponsor:

国家:

中国

省(直辖市):

河南

市(区县):

郑州

Country:

China

Province:

Henan

City:

zhengzhou

单位(医院):

郑州大学公共卫生学院

具体地址:

河南省郑州市高新区科学大道100号郑州大学新校区公共卫生学院

Institution
hospital:

College of Public Health in Zhengzhou University

Address:

College of Public Health in Zhengzhou University; 100 Kexue Road, Gaoxin District, Zhengzhou, Henan, China

经费或物资来源:

国家重点研发计划“精准医学研究”重点专项 

Source(s) of funding:

National Key Research and Development Program “Precision Medicine Initiative” of China 

研究疾病:

糖尿病、肥胖、高血压、血脂异常、冠心病、脑卒中等心血管代谢性疾病、骨质疏松和心理疾病 

Target disease:

diabetes mellitus, obesity, hypertension,dyslipidemia,coronary heart disease,stroke,osteoporosis,and mental disorders 

研究疾病代码:

 

Target disease code:

 

研究类型:

观察性研究 

Study type:

Observational study 

研究所处阶段:

其它 

Study phase:

N/A 

研究目的:

建立和完善不同区域农村人群监测网络,了解我国农村人群中慢性非传染病的发病情况,掌握常见慢性病的影响因素及常见慢性病的动态变化趋势。加强以农村为基础的预防基地建设,培训基层医务人员,大力发展健康教育。预测中国农村人群常见慢性病发病情况及流行趋势,并提出适合中国人群特点的有效防治策略和措施还有通过健康教育倡导人们自行改变生活方式,以降低人群常见慢性病的发病率和死亡率,减少人们常见慢性病负担,同时建立常见慢性疾病健康风险评估模型,评估个体常见慢性病发生风险,以期早期开展常见慢性病防治。 

Objectives of Study:

The main goal of the current study was to examine the burden of stroke, coronary heart disease, cancer, diabetes mellitus, hypertension, dyslipidemia, obesity, osteoporosis, mental disorders, and other chronic diseases in rural populations, to explore potential genetic, behavioral, and environmental risk factors, to illuminate the common non-communicable chronic diseases trends, to investigate gene–behavior–environment interactions, and to develop and evaluate the risk scores models. 

药物成份或治疗方案详述:

 

Description for medicine or protocol of treatment in detail:

 

研究设计:

队列研究 

Study design:

Cohort study 

纳入标准:

1.18-79岁当地常住农村居民 2. 参加者本人及其家属同意其参加本研究,并签署知情同意书 

Inclusion criteria

1. The local rural adult residents aged 18-79 year old 2. All participants signed the informed consents 

排除标准:

1.抽血恐惧者 2.传染病患者,例如艾滋病、结核病患者 3.精神病患者 

Exclusion criteria:

1. People with criteria blood phobia; 2. Patients with infectious diseases, such as HIV/AIDS, tuberculosis. 3. Psychopath. 

研究实施时间:

Study execute time:

From2015-01-01To 2020-12-31 

干预措施:

Interventions:

组别:

1

样本量:

10000

Group:

Experimental group

Sample size:

干预措施:

健康教育

干预措施代码:

Intervention:

Health education

Intervention code:

组别:

2

样本量:

25000

Group:

Control group

Sample size:

干预措施:

干预措施代码:

Intervention:

No

Intervention code:

研究实施地点:

Countries of recruitment and research settings:

国家:

中国 

省(直辖市):

河南 

市(区县):

许昌 

Country:

China 

Province:

Henan 

City:

Xuchang 

单位(医院):

许昌市疾病预防控制中心 

单位级别:

市级 

Institution
hospital:

Xuchang Center for Disease Control and Prevention  

Level of the institution:

city 

国家:

中国 

省(直辖市):

河南 

市(区县):

开封 

Country:

China 

Province:

Henan 

City:

Kaifeng 

单位(医院):

开封市疾病预防控制中心 

单位级别:

市级 

Institution
hospital:

Kaifeng Center for Disease Control and Prevention  

Level of the institution:

city 

国家:

中国 

省(直辖市):

河南 

市(区县):

驻马店 

Country:

China 

Province:

Henan 

City:

Zhumadian 

单位(医院):

驻马店市疾病预防控制中心 

单位级别:

市级 

Institution
hospital:

Zhumadian Center for Disease Control and Prevention  

Level of the institution:

city 

国家:

中国 

省(直辖市):

河南 

市(区县):

三门峡 

Country:

China 

Province:

Henan 

City:

Sanmenxia 

单位(医院):

三门峡市疾病预防控制中心 

单位级别:

市级 

Institution
hospital:

Sanmenxia Center for Disease Control and Prevention  

Level of the institution:

city 

国家:

中国 

省(直辖市):

河南 

市(区县):

新乡 

Country:

中国 

Province:

Henan 

City:

Xinxiang 

单位(医院):

新乡市疾病预防控制中心 

单位级别:

市级 

Institution
hospital:

Yuzhou Center for Disease Control and Prevention  

Level of the institution:

City 

测量指标:

Outcomes:

指标中文名:

空腹血糖

指标类型:

主要指标 

Outcome:

Fasting serum glucose

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

总胆固醇

指标类型:

主要指标 

Outcome:

TC

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

高密度脂蛋白胆固醇

指标类型:

主要指标 

Outcome:

HDL-C

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

低密度脂蛋白胆固醇

指标类型:

主要指标 

Outcome:

LDL-C

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

甘油三酯

指标类型:

主要指标 

Outcome:

TG

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

血肌酐

指标类型:

主要指标 

Outcome:

creatinine

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

血尿素

指标类型:

主要指标 

Outcome:

urea

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

胰岛素

指标类型:

主要指标 

Outcome:

Insulin

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

超敏C反应蛋白

指标类型:

主要指标 

Outcome:

Hypersensitive c-reactive protein

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

C-肽

指标类型:

主要指标 

Outcome:

C-P

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

尿常规

指标类型:

主要指标 

Outcome:

Urine Routine

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

尿微量白蛋白

指标类型:

主要指标 

Outcome:

Urinary albumin

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

身高

指标类型:

主要指标 

Outcome:

Height

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

体重

指标类型:

主要指标 

Outcome:

Weight

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

腰围

指标类型:

主要指标 

Outcome:

Waist circumference

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

臀围

指标类型:

主要指标 

Outcome:

Hip circumference

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

血尿酸

指标类型:

主要指标 

Outcome:

Uric Acid

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

血常规

指标类型:

主要指标 

Outcome:

blood routine

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

心电图

指标类型:

主要指标 

Outcome:

Electrocardiogram

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

握力

指标类型:

主要指标 

Outcome:

Grip strength

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

B超

指标类型:

主要指标 

Outcome:

Abdominal B-type ultrasound inspection

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

胸部X光

指标类型:

主要指标 

Outcome:

Chest X-ray

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

身体脂肪率

指标类型:

主要指标 

Outcome:

Body fat percentage

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

内脏脂肪指数

指标类型:

主要指标 

Outcome:

Visceral fat index

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

肺功能

指标类型:

主要指标 

Outcome:

Pulmonary function

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

骨密度

指标类型:

主要指标 

Outcome:

Bone mineral density

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

糖化血红蛋白

指标类型:

主要指标 

Outcome:

Glycosylated hemoglobin

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

基础代谢率

指标类型:

主要指标 

Outcome:

Basal metabolic rate

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

血压

指标类型:

主要指标 

Outcome:

Resting blood pressure

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

心率

指标类型:

主要指标 

Outcome:

Heart rate

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

谷丙转氨酶

指标类型:

主要指标 

Outcome:

ALT

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

谷草转氨酶

指标类型:

主要指标 

Outcome:

AST

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

碱性磷酸酶

指标类型:

主要指标 

Outcome:

ALP

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

总胆红素

指标类型:

主要指标 

Outcome:

TBIL

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

直接胆红素

指标类型:

主要指标 

Outcome:

DBIL

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

间接胆红素

指标类型:

主要指标 

Outcome:

IBIL

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

尿肌酐

指标类型:

主要指标 

Outcome:

urine creatinine

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

有机磷农药

指标类型:

主要指标 

Outcome:

organophosphorus pesticide

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

有机氯农药

指标类型:

主要指标 

Outcome:

organochlorine pesticide

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

氨基甲酸酯类农药

指标类型:

主要指标 

Outcome:

n-methylcarbamates pesticides

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

金属元素

指标类型:

主要指标 

Outcome:

Metal elements

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

指标中文名:

激素

指标类型:

主要指标 

Outcome:

Hormone levels

Type:

Primary indicator 

测量时间点:

测量方法:

Measure time point of outcome:

Measure method:

采集人体标本:

Collecting sample(s)
from participants:

标本中文名:

组织:

肘静脉

Sample Name:

blood

Tissue:

ulnar vein

人体标本去向

使用后保存 

说明

20

Fate of sample:

Preservation after use 

Note:

标本中文名:

尿

组织:

Sample Name:

urine

Tissue:

kidney

人体标本去向

使用后保存 

说明

20

Fate of sample:

Preservation after use 

Note:

标本中文名:

粪便

组织:

Sample Name:

Feces

Tissue:

人体标本去向

使用后保存 

说明

20

Fate of sample:

Preservation after use 

Note:

征募研究对象情况:

Recruiting status:

正在进行

Recruiting

年龄范围:

Participant age:

最小 Min age 18 years
最大 Max age 79 years

性别:

男女均可

Gender:

Both

随机方法(请说明由何人用什么方法产生随机序列):

整群抽样

Randomization Procedure (please state who generates the random number sequence and by what method):

cluster random sampling

盲法:

Blinding:

试验完成后的统计结果(上传文件):

点击下载

Calculated Results after
the Study Completed(upload file):

download

原始数据公开时间:

The time of sharing IPD:

即时公开/Real time access

共享原始数据的方式(说明:请填入公开原始数据日期和方式,如采用网络平台,需填该网络平台名称和网址):

郑州大学公共卫生学院

The way of sharing IPD”(include metadata and protocol, If use web-based public database, please provide the url):

College of Public Health in Zhengzhou University

数据采集和管理(说明:数据采集和管理由两部分组成,一为病例记录表(Case Record Form, CRF),二为电子采集和管理系统(Electronic Data Capture, EDC),如ResMan即为一种基于互联网的EDC:

郑州大学公共卫生学院

Data collection and Management (A standard data collection and management system include a CRF and an electronic data capture:

College of Public Health in Zhengzhou University

数据管理委员会:

Data Managemen Committee:

暂未确定/Not yet

注册人:

Name of Registration:

 2015-07-06
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